裴玉新

女， 西北農(nóng)林科技大學， 教授/研究員/教授級高工或同等級別

學習/工作經(jīng)歷

1.學習經(jīng)歷

(1) 1984-09至1988-06，鄭州大學，化學，學士；

(2) 1988-09至1991-06，鄭州大學，化學，碩士；

(3) 1995-02至1998-03，東華大學，化學纖維專業(yè)，博士；

2.工作經(jīng)歷

(1) 1998-04至2000-04，浙江大學，博士后；

(2) 2000-05至2001-12，Lund University，博士后；

(3) 2002-01至2003-03，Technical University of Denmark，博士后；

(4) 2003-04至2010-06，Royal Institute of Technology，博士后；

(5) 2006-06至2007-06，Universitatsklinikum Heidelberg，博士后；

(6) 1991-10至1994-10，鄭州大學，材料系，助教；

(7) 1994-11至1995-01，鄭州大學，材料系，講師；

(8) 2010-07至2016-12，西北農(nóng)林科技大學，理學院，教授；

(9) 2017-01至今，西北農(nóng)林科技大學，化學與藥學院化學系，教授。

研究領域和興趣

基于超分子化學的智能納米功能材料的構筑及應用： 1.糖基靶向藥物遞送系統(tǒng)； 2.有機-無機雜化納米藥物； 3.藥物實時示蹤、腫瘤細胞檢測及生物成像。

主要業(yè)績

三級教授，博士生導師。多年來致力于超分子自組裝和靶向藥物遞送研究，已在基于可控超分子組裝實現(xiàn)“智能”糖靶向納米藥物載體的構建及其應用于靶向腫瘤研究方面取得了系列創(chuàng)新性研究成果，在Angew. Chem. Int. Ed., Adv. Sci, Adv. Funct. Mater. Chem Sci. 等國際著名期刊發(fā)表高水平論文100余篇，主持國家級、省部級等研究課題10余項，獲批發(fā)明專利6項。中國生物化學與分子生物學會復合糖專業(yè)委員會委員，中國生化制藥工業(yè)協(xié)會糖類藥物分會專家委員會委員。

代表成果

1.Jiaxuan Li, Yanqing Li, Yi Wang, Wenjuan Jin, Zhichao Pei*, Yinghua Lv*, and Yuxin Pei*. A proton pump inhibitor-programmed ROS generator enhances the synergistic efficacy of chemo-/chemodynamic therapy with reduced renal injury, Chem. Eng. J., 159201 (505) (2025). DOI: 10.1016/j.cej.2024.159201；
2.Jiaxuan Li, Zelong Chen, Zhichao Pei*, Yuxin Pei*. A hyaluronic acid modified advanced nanoagent activated by tumor microenvironment enables a reciprocal dual-modality therapy. Chem. Eng. J., 159884 (507) (2025). DOI: 10.1016/j.cej.2025.159884；
3.Shangqian Zhang, Jiaxuan Li, Xuan Hu, Zelong Chen, Junliang Dong, Chenhao Hu, Shuang Chao, Yinghua Lv, Yuxin Pei*, Zhichao Pei*. H2S and NIR light-driven nanomotors induce disulfidptosis for targeted anticancer therapy by enhancing disruption of tumor metabolic symbiosis. Chin. Chem. Lett., 110314 (36) (2025). DOI: 10.1016/j.cclet.2024.110314；
4.Yi Wang, Zelong Chen, Jiahui Li, Yafei Wen, Jiaxuan Li, Yinghua Lv, Zhichao Pei,* Yuxin Pei*. A paramagnetic metal-organic framework enhances mild magnetic hyperthermia therapy by downregulating heat shock proteins and promoting ferroptosis via aggravation of two-way regulated redox dyshomeostasis. Adv. Sci, 306178, (11) (2023), DOI: 10.1002/advs.202306178；
5.Jiaxuan Li, Baifei Hu, Zelong Chen, Jiahui Li, Wenjuan Jin, Yi Wang, Yichen Wan，Yinghua Lv，Yuxin Pei,* Hongtao Liu,* Zhichao Pei*. Mn (III)-mediated carbon-centered radicals generate an enhanced immunotherapeutic effect. Chem Sci. 15, 765-777 (15) (2023), DOI: 10.1039/d3sc03635a；
6.Yun Qu, Wenjuan Jin, Yichen Wan, Zhichao Pei, Yuxin Pei*. J-aggregation of photosensitizers leads to an ultrahigh drug-loading system for targeted delivery. Chin. Chem. Lett., 108493 (35) (2024). DOI: 10.1016/j.cclet.2023.108493；
7.Xiaojiao Di, Zhichao Pei, Yuxin Pei*, Tony D. James*. Tumor microenvironment-oriented MOFs for chemodynamic therapy. Coord. Chem. Rev. 2023, 484: 215098 (484) (2023). DOI: 10.1016/j.ccr.2023.215098；
8.Jiaxuan Li, Xiaomeng Lv, Jiahui Li, Wenjuan Jin, Zelong Chen, Yafei Wen, Zhichao Pei and Yuxin Pei*. A supramolecular near-infrared nanophotosensitizer from host-guest complex of lactose-capped pillar[5]arene with aza-BODIPY derivative for tumor eradication. Org. Chem. Front., 1927-1935 (10) (2023). DOI: 10.1039/d3qo00065f；
9.Yincheng Chang,? Yinghua Lv,? Peng Wei, Pengfei Zhang, Liang Pu, Xiaoxu Chen, Kui Yang, Xueliang Li, Yuchao Lu, Chenxi Hou, Yuxin Pei,* Wenxian Zeng,* Zhichao Pei*. Multifunctional glyco nanofibers: siRNA induced supermolecular assembly for codelivery in vivo. Adv Funct Mater, 1703083 (27) (2017). DOI: 10.1002/adfm.201703083;
10.Yincheng Chang, Kui Yang, Peng Wei, Sisi Huang, Yuxin Pei,* Wei Zhao, Zhichao Pei*. Cationic vesicles based on amphiphilic pillar[5]arene capped with ferrocenium: A redox-responsive system for drug/siRNA co-delivery. Angew. Chem. Int. Ed, 13126-13130 (53) (2014). DOI: 10.1002/ange.201407272;

*以上信息由高級會員個人更新和維護。