裴志超

男， 西北農(nóng)林科技大學(xué)， 教授/研究員/教授級(jí)高工或同等級(jí)別

學(xué)習(xí)/工作經(jīng)歷

(1) 1984 - 1988 鄭州大學(xué)化學(xué)系化學(xué)專(zhuān)業(yè)，理學(xué)學(xué)士；

(2) 1988–1990 鄭州市第二化肥廠碳化工段工段長(zhǎng)；

(3) 1990–1995 鄭州市化工三廠新產(chǎn)品車(chē)間主任；

(4) 1996–1997 鄭州市化工三廠廠長(zhǎng)；

(5) 1998–2000 浙江大學(xué)膜分離工程公司工程師；

(6) 2002 - 2006 瑞典皇家工學(xué)院化學(xué)化工學(xué)院化學(xué)系有機(jī)化學(xué)專(zhuān)業(yè)，博士；

(7) 2007–2010 瑞典Attana生物傳感器公司高級(jí)研究員、生物芯片研發(fā)部經(jīng)理；

(8) 2010.07至今 西北農(nóng)林科技大學(xué)“后稷學(xué)者”特聘教授；

研究領(lǐng)域和興趣

研究領(lǐng)域?yàn)榛诜肿幼越M裝構(gòu)建超分子糖功能納米材料以及其在生物醫(yī)藥領(lǐng)域的應(yīng)用；糖化學(xué)生物學(xué)、納米生物醫(yī)藥、和基于QCM生物傳感器技術(shù)的生物芯片的研究及應(yīng)用。具體研究方向包括糖納米藥物和靶向藥物遞送的研究、以及熒光功能材料在生物醫(yī)學(xué)（藥物示蹤、診斷和檢測(cè)）中的應(yīng)用等研究。

主要業(yè)績(jī)

二級(jí)教授，博士生導(dǎo)師，研究領(lǐng)域?yàn)榛诜肿幼越M裝構(gòu)建超分子糖功能納米材料以及其在生物醫(yī)藥領(lǐng)域的應(yīng)用；納米生物醫(yī)藥和糖化學(xué)生物學(xué)，具體研究方向包括糖納米藥物和靶向藥物遞送的研究、以及熒光功能材料在生物醫(yī)學(xué)（藥物示蹤、診斷和檢測(cè)）中的應(yīng)用等研究，并取得了系列創(chuàng)新性研究成果，在 Angew. Chem. Int. Ed.、Adv. Sci.、Adv. Funct. Mater.、Chem Sci. 等國(guó)際著名期刊發(fā)表高水平研究論文 100 余篇，其中影響因子8.0以上 32 篇。獲批國(guó)家發(fā)明專(zhuān)利 5 項(xiàng)。主持國(guó)家級(jí)、省部級(jí)及企業(yè)橫向課題等研究課題16項(xiàng)，其中，國(guó)家自然科學(xué)基金面上項(xiàng)目 4 項(xiàng)，國(guó)家外國(guó)專(zhuān)家項(xiàng)目1項(xiàng)。作為大會(huì)主席舉辦國(guó)際會(huì)議1次。中國(guó)化學(xué)會(huì)糖化學(xué)專(zhuān)業(yè)委員會(huì)委員，中國(guó)生物物理學(xué)會(huì)糖生物學(xué)分會(huì)委員會(huì)委員，中國(guó)生物工程學(xué)會(huì)糖生物工程專(zhuān)業(yè)委員會(huì)委員，中國(guó)生物化學(xué)與分子生物學(xué)會(huì)復(fù)合糖專(zhuān)業(yè)委員會(huì)委員，中國(guó)生化制藥工業(yè)協(xié)會(huì)糖類(lèi)藥物分會(huì)專(zhuān)家委員會(huì)委員。擔(dān)任國(guó)際學(xué)術(shù)期刊《Frontiers in Chemistry》副主編?！丁爸A友華”農(nóng)科高素質(zhì)來(lái)華留學(xué)研究生教育模式探索與實(shí)踐》成果榮獲2022年國(guó)家級(jí)教學(xué)成果二等獎(jiǎng)（第一完成人）

代表成果

1.Yi Wang, Zelong Chen, Jiahui Li, Yafei Wen, Jiaxuan Li, Yinghua Lv, Zhichao Pei,* Yuxin Pei*. A paramagnetic metal-organic framework enhances mild magnetic hyperthermia therapy by downregulating heat shock proteins and promoting ferroptosis via aggravation of two-way regulated redox dyshomeostasis. Adv. Sci, 306178, (11) (2023), DOI: 10.1002/advs.202306178;
2.Jiaxuan Li, Baifei Hu, Zelong Chen, Jiahui Li, Wenjuan Jin, Yi Wang, Yichen Wan，Yinghua Lv，Yuxin Pei,* Hongtao Liu,* Zhichao Pei*. Mn (III)-mediated carbon-centered radicals generate an enhanced immunotherapeutic effect. Chem Sci, 765-777 (15) (2024), DOI: 10.1039/d3sc03635a;
3.Shuang Chao, Pei Huang, Ziyan Shen, Yuxin Pei, Yinghua Lv, Yuchao Lu, Zhichao Pei*. A mannose-functionalized pillar[5]arene-based supramolecular fluorescent probe for real-time monitoring of gemcitabine delivery to cancer cells. Org. Chem. Front, 3491-3497 (10) (2023). DOI: 10.1039/d3qo00476g;
4.Ziyan Shen, Ning Ma, Feng Wang, Jiaming Ren, Chenxi Hou, Shuang Chao, Yuxin Pei, Zhichao Pei*. pH- and H2O2-sensitive drug delivery system based on sodium xanthate: Dual-responsive supramolecular vesicles from one functional group. Chinese Chem. Lett. 4563-4566 (123) (2022). DOI: 10.1016/j.cclet.2022.01.069;
5.Ke Ma, Jingtao Shi, Yuxin Pei, Zhichao Pei*. A carrier-free supramolecular nanoprodrug based on lactose-functionalized dimeric camptothecin via self-assembly in water for targeted and fluorescence imaging-guided chemo-photodynamic therapy. J. Colloid Interf. Sci. 353-363 (609) (2021). DOI: 10.1016/j.jcis.2021.12.002;
6.Junliang Dong, Yueyuan Yu, Yuxin Pei, Zhichao Pei*. pH-responsive aminotriazole doped metal organic frameworks nanoplatform enables self-boosting reactive oxygen species generation through regulating the activity of catalase for targeted chemo/chemodynamic combination therapy. J. Colloid Interf. Sci, 1651-1660 (607) (2021). DOI: 10.1016/j.jcis.2021.09.043;
7.Weiwei Feng, Yinghua Lv, Zelong Chen, Feng Wang, Yi Wang, Yuxin Pei,* Wenjuan Jin, Chaojie Shi, Yang Wang, Yun Qu, Wei Ji, Liang Pu, Xue-Wei Liu,* Zhichao Pei*. A carrier-free multifunctional nano photosensitizer based on sel Chem. Eng. J, 129178 (417) (2021). f-assembly of lactose-conjugated BODIPY for enhanced anti-tumor efficacy of dual phototherapy. DOI: 10.1016/j.cej.2021.129178;
8.Xueming Li, Siyu Song, Yuxin Pei, Hai Dong,* Teodor Aastrup, Zhichao Pei*. Direct attachment of suspension cells to PDA surface and its application in suspension-cell QCM biosensor. Sensor Actuat. B-Chem, 128823 (326) (2021). DOI: 10.1016/j.snb.2020.128823;
9.Yincheng Chang,? Yinghua Lv,? Peng Wei, Pengfei Zhang, Liang Pu, Xiaoxu Chen, Kui Yang, Xueliang Li, Yuchao Lu, Chenxi Hou, Yuxin Pei,* Wenxian Zeng,* Zhichao Pei*. Multifunctional glyco nanofibers: siRNA induced supermolecular assembly for codelivery in vivo. Adv Funct Mater, 1703083 (27) (2017). DOI: 10.1002/adfm.201703083;
10.Yincheng Chang, Kui Yang, Peng Wei, Sisi Huang, Yuxin Pei,* Wei Zhao, Zhichao Pei*. Cationic vesicles based on amphiphilic pillar[5]arene capped with ferrocenium: A redox-responsive system for drug/siRNA co-delivery. Angew. Chem. Int. Ed, 13126-13130 (53) (2014). DOI: 10.1002/ange.201407272;

*以上信息由高級(jí)會(huì)員個(gè)人更新和維護(hù)。