谷曉霞

女， 皖南醫(yī)學(xué)院， 教授/研究員/教授級(jí)高工或同等級(jí)別

學(xué)習(xí)/工作經(jīng)歷

1994-09至1998-07，安徽師范大學(xué)，化學(xué)教育，學(xué)士；2004-09至2007-06，安徽師范大學(xué)，有機(jī)化學(xué)，碩士；2010-09至2015-12，安徽師范大學(xué)，有機(jī)化學(xué)，博士；2016-9至2017-7，安徽師范大學(xué)，化學(xué)與材料學(xué)院，訪學(xué)；2021-9至2022-7，南京大學(xué)，化學(xué)化工學(xué)院，訪學(xué)。
1998.07-2000.08，宣城中學(xué)，中二；2000-09至2003-09，皖南醫(yī)學(xué)院，基礎(chǔ)醫(yī)學(xué)院，助教；2003-09至2008-12，皖南醫(yī)學(xué)院，基礎(chǔ)醫(yī)學(xué)院，講師；2008-12至2017-11，皖南醫(yī)學(xué)院，基礎(chǔ)醫(yī)學(xué)院，副教授；2017-11至今，皖南醫(yī)學(xué)院，藥學(xué)院，教授

研究領(lǐng)域和興趣

有機(jī)化學(xué)；金屬有機(jī)化學(xué)；金屬化學(xué)生物學(xué)

主要業(yè)績(jī)

皖南醫(yī)學(xué)院，藥學(xué)院，博士，教授，生物物理學(xué)碩導(dǎo)，校第二批學(xué)術(shù)和技術(shù)帶頭人后備人選。研究方向：生物活性小分子及熒光探針設(shè)計(jì)與合成，主持國(guó)家自然科學(xué)青年基金項(xiàng)目1項(xiàng)，安徽省高校重點(diǎn)項(xiàng)目2項(xiàng)，發(fā)表論文30余篇，其中，SCI收錄20余篇。

代表成果

(1) Chunfei Wang, Lei Hu, Jing Yang, Jie Wang, Yuqing Wang, Xiaoxia Gu*, Hui Wang*. Brominated alkyl promotes a red-emissive probe track lipid droplets in cells and fatty liver. Microchemical Journal, 2024. 201: p. 110591.DOI: 10.1016/j.microc.2024.110591
(2) Jing Yang, Yuqing Wang, Zhiyu Wang, Jie Wang, Cuifeng Zhang, Xiaoxia Gu*, Lei Hu*, Hui Wang*. Multifunctional lipid droplet probes for observing the polarity change of ferroptosis, inflammation, fatty liver and evaluating the efficacy of drugs. Analytica Chimica Acta, 2024. 1312: p. 342747.DOI: 10.1016/j.aca.2024.342747
(3) Lei Hu, Liping Su, Zhiyu Wang, Jing Yang, Yuqing Wang, Jie Wang, Xiaoxia Gu*, Hui Wang*. Application of acid-activated near-infrared viscosity fluorescent probe targeting lysosomes in cancer visualization. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024. 323: p. 124918.DOI: 10.1016/j.saa.2024.124918
(4) Zhiyu Wang,Yi Deng, Jiayi Ge, Feiyang Ding, Hailing Du, Xuebin Shen, Cuifeng Zhang, Xiaoxia Gu, Lei Hu*, Hui Wang*. Aggregation-induced emission fluorogenic probes for wash-free imaging of lipid droplets in living cells. Tetrahedron Letters, 2024. 141: p. 155070.DOI: 10.1016/j.tetlet.2024.155070
(5) Zhiyu Wang, Yi Deng, Jie Wang, Jiayi Ge, Fan Lv, Jiangfei Li, Cuifeng Zhang, Xiaoxia Gu, Lei Hu*, Hui Wang*. Polarity-sensitive fluorescent probe based on coumarin derivatives for imaging lipid droplets and diagnosis of non-alcoholic fatty liver. Journal of Molecular Structure, 2024. 1314: p. 138843. DOI: 10.1016/j.molstruc.2024.138843
(6) Hui Wang, Xuebin Shen, Jiayi Ge, Yi Deng, Feiyang Ding, Zhiyu Wang, Wenya Zhu, Lei Hu, Jing He, Xiaoxia Gu. Rational design of AIE-based carbazole derivatives for lipid droplet- specific imaging in living cells, Chemical Papers, 2022, 77(1): 563-569.DOI: 10.1007/s11696-022-02515-3
(7)Hui Wang, Cuifeng Zhang, Xuebin Shen, Zhiyu Wang, Jing Yang, Shuting Shen, Lei Hu, Jin Pan, Xiaoxia Gu. Rational design AIE fluorescent probes for wash-free and lipid droplet specific imaging of fatty liver based on coumarin, Dyes and Pigments, 2023, 212: 111137.DOI: 10.1016/j.dyepig.2023.111137
(8)吳靜，惠樸真，鄭慧林，袁平川，汪春飛，王慧*，谷曉霞*. 萘酚醛席夫堿過(guò)渡金屬配合物的合成、晶體結(jié)構(gòu)及抗腫瘤活性，無(wú)機(jī)化學(xué)學(xué)報(bào)，2024,40(12):2422-2428. DOI：10.11862/CJIC.20240278

*以上信息由高級(jí)會(huì)員個(gè)人更新和維護(hù)。